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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T79083 |
HSP90-IN-22
|
HSP | Cytoskeletal Signaling; Metabolism |
HSP90-IN-22(Compound 35)作为Hsp90抑制剂,对MCF7乳腺癌细胞的IC50为3.65μM,对SKBr3乳腺癌细胞的IC50为2.71μM,显示出对这些细胞系具有显著的抗增殖活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01382 |
HSPB8 Protein, Human, Recombinant (His)
Small stress protein-like protein HSP22,CR... |
Human | E. coli |
Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have bee... |